Inventors: Ebarvia BS
, Ubando IH
Tetracycline-imprinted polymer sensor based on piezoelectric quartz crystal
Publication date: 2018
The synthesis of a molecularly imprinted polymer (MIP) for tetracycline was done via precipitation polymerization at 60 °C for 24 h. Methacrylic acid was used as monomer, trimethylolpropane methacrylate (TRIM) as the crosslinker, 2,2-azobis-isobutylonitrile (AIBN) as the initiator and dichloromethane as porogen and tetracycline HCI as the template. The template was extracted from the polymer by soxhlet extraction using methanol-acetic acid. The MIP is used as sensing layer in a piezoelectric quartz crystal transducer. Binding of tetracycline in the said sensor with MIP coating is indicated by a corresponding decrease in the frequency response of the piezoelectric quartz crystal.
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